organization:PATH
Location: South San Francisco, California, United States
Tracking Code 5695
Job Description
PATH is an international nonprofit organization that transforms global health through innovation. We take an entrepreneurial approach to developing and delivering high-impact, low-cost solutions, from lifesaving treatments, vaccines and devices to collaborative programs with communities. Through our work in more than 70 countries, PATH and our partners empower people to achieve their full potential.
PATH's Drug Development Program is working to discover, develop, and deliver safe, effective, and affordable new treatments for diseases disproportionately affecting people in the developing world. By combining entrepreneurial energy, pharmaceutical expertise, and an innovative product development partnership model, we challenge the assumption that pharmaceutical research and development is too expensive to create the new medicines that the developing world desperately needs.
The Drug Development Program's Pre-clinical Studies Group has an excellent opportunity for a new Drug Development Scientist to focus primarily on treatments for diarrheal diseases. S/he will be one of 5 scientists in the team who create research plans, design and execute experiments, and analyze and report results of key scientific findings for publication and for new grant applications.
The Drug Development Scientist will establish a strong working knowledge of the current literature and technology pertinent to the research activities. S/he will also provide scientific evaluation of new lead drug candidates, and potentially lead efforts to submit grant applications in support of future research efforts.
ESSENTIAL DUTIES AND RESPONSIBILITIES include the following, other duties may be assigned:
- Applies fundamental scientific principles in understanding and communicating complex scientific issues related to diarrheal diseases; plans and conducts research and preclinical studies to support diarrheal disease project(s).
- Designs and implements key scientific experiments to support the understanding and validation of drug mechanisms of action.
- When necessary, works with and monitors the work of outside consultants, CROs, and academic institutions to design and implement key studies including ADME and pharmacokinetic/ pharmacodynamic studies to support the development and regulatory filing of drug candidates.
- Establishes a strong working knowledge of literature and technology pertinent to current research activities and recommends improvements/ innovations in response to identified needs; prepares reviews of relevant literature on new diseases and technologies to support decision-making.
- Provides scientific evaluation and input on new project opportunities in area of expertise and prepares, plans, compiles, writes and edits technical grant proposals.
- International or domestic travel may be required up to 25%.
Required Skills
The successful candidate will have:
- Proven quantitative analysis and documentation skills as well as excellent attention to detail.
- Demonstrated ability to analyze and summarize results in written scientific reports and manuscripts.
- Proven ability to design, implement, and supervise preclinical research studies in support of mechanistic investigations, discovery, and pre-clinical/early stage clinical development efforts.
- Excellent written and verbal communication skills, with the ability to effectively communicate experimental results to audiences with technical and non-technical backgrounds.
- Flexible and highly motivated team player with the ability to manage multiple priorities in a matrixed environment.
- Ability to build productive cross-functional research collaborations with public and private sector partners.
- MS Office, MS Excel and MS Project proficiency is required.
Required Experience
A doctoral degree in biomedical sciences is required, with 5 or more years of relevant experience in drug development, biotechnology, clinical research or related field. Experience researching animal models of disease, and in the design and conduct of pharmacology and/or toxicology studies. Direct experience preparing FDA Investigational New Drug applications and other regulatory filings. Experience in gastrointestinal physiology and infectious diarrheal diseases. Drug development team or sub-team leadership experience is a plus. Demonstrated project management experience with a track record of delivering results on time and according to budget constraints.
PATH is dedicated to diversity and is an equal opportunity employer.
Job Location South San Francisco, California, United States Position Type Full-Time/Regular
How to Apply
http://unjobs.org/vacancies/1375736039795